Larvae of the codling moth (CM), Cydia pomonella, bore into unripe apples and complete their development inside up to the last larval stage, resulting in non-marketable fruits and high economic damage. In organic and integrated pome fruit production, different Cydia pomonella granulovirus (CpGV) products are successfully used to reduce infestation and avoid fruit damage.

Some years ago, CpGV resistant CM populations were recognized in Europe and recently also in the USA. Resistance-breaking CpGV isolates have been detected and solved the resistance problem. However, little is known about the molecular resistance mechanism(s). In a new research project, supported by the DFG, the molecular basics of CpGV resistance will be investigated.

The final outcome can answer the question how the codling moth blocks CpGV replication at an early stage of infection. Elucidating the mechanism of CpGV resistance to codling moth will not only address scientific questions but also directs the way for a further sustainable use of CpGV in pome fruit production.